The wear and tear of a truly remarkable season finally took its toll on Novak Djokovic today as Andy Murray stunned the No. 1-ranked Serb in the finals of the Western & Southern Open in sultry Cincinnati. Murray led 6-4, 3-0 when a fatigued Djokovic retired with a shoulder injury just minutes before a downpour drenched Center Court at the Linder Family Tennis Center. The title was Murray’s second of the year and 18th of his career, and his seventh Masters Series championship. The loss snapped Djokovic’s 16-match winning streak and dropped the Serb’s record to 57-2 on the year. World No. 4 Murray broke Djokovic in the opening game of the match, but dropped served in the sixth game to level things up at 3-3. The match turned in the next game, though, when Murray broke back, cashing the crucial break point after a 42-shot rally. Djokovic would win one more game before retiring midway through the second set. Murray served impeccably, winning 84 percent of his first service points, while committing only 11 unforced errors to 31 for Djokovic. The Scot was clearly the more rested of the two. He lost in the opening round of the Rogers Cup in Montreal last week, giving him unexpected time to work on his game. The break obviously helped as Murray didn’t lose a set all week in Cincinnati. “I had five or six days to get ready here,” said Murray, who won his first Masters Series championship in Cincinnati in 2008. “I’ve always played well on this court.” Djokovic, last week’s Rogers Cup champion, was looking to pull off a Masters Series double for the third time this season, having won back-to-back at Indian Wells and Miami, and Rome and Madrid. “I just could not serve. I served an average 90 miles per hour the first serve, and I could not play forehands,” Djokovic said. “I could have maybe played another couple of games, but what for? I cannot beat a player like Murray today with one stroke.” Djokovic was philosophical about the loss. “There is no good loss, that’s for sure. But the good thing is that there is a week, eight days [before] the start of the US Open. So I think that’s enough time for me to get ready.” Murray improved to 4-6 against Djokovic.